There are various accidents and rifts on-stage (a fight between the cast, Grolton inadvertently hitting Jules in the face). In order to avoid confusion with the soap opera (also entitled "Long Road to Ruin") and the "real world", the scenes in the soap opera have brown tones to make it more vintage, while the real world retains normal color. Actress Rashida Jones guest stars as "Racinda Jules" ("Susan Belfontaine", the doctor's love interest). Bassist Nate Mendel plays "Ned Bender" ("Saul Goode", the show's shady antagonist).
Guitarist Chris Shiflett plays "Christopher Mishomotohama" ("Little Jimmy", a severely injured child). Drummer Taylor Hawkins plays "Ty Hawkstone" ("Les Groper", Davidoff's womanizing colleague). Grohl plays "Davy Grolton", who stars as the main doctor, "Hansom Davidoff". As seen in the opening credit sequence, the Foo Fighters portray the actors who in turn portray the show's characters. The music video of the song, directed by Jesse Peretz (who also has directed previous Foo Fighters videos "Big Me" and "Learn To Fly"), is a comedic spoof of a stereotypical 1970s-era hospital soap opera ( General Hospital in particular), and is essentially a " show within a show". " Holiday in Cambodia" ( Dead Kennedys cover, live from MTV Video Music Awards 2007, featuring Serj Tankian)." Big Me" (Live from Wal-Mart soundcheck)." Keep the Car Running" ( Arcade Fire cover, live from Brighton 18 August 2007).In the United Kingdom, "Long Road to Ruin" peaked in the top 40 of the UK Singles Chart and number one on the UK Rock Chart. The song's number-one position on the Modern Rock chart, gave the Foo Fighters a record-setting feat by becoming the first act to reach number one on the chart in each of four consecutive years. It peaked at number 89 on the Billboard Hot 100. "Long Road to Ruin" topped the Billboard Modern Rock Tracks chart for seven consecutive weeks and reached number two on the Mainstream Rock Tracks in early 2008.
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